Terms you need to know about respiration and oxygenation
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Ventilation |
The movement of air in and out of the lungs |
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Perfusion |
The movement of blood into and out of the lungs |
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Pulmonary circuit |
The path of blood from the heart to the lungs and back again |
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Surfactant |
The soapy coating that lines the alveoli, making them easier to inflate |
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Dead space |
The parts of the respiratory tract that don’t pass O2 to the blood |
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Accessory muscles |
The muscles besides the diaphragm that are used to inhale and exhale |
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Pleural cavity |
The cavity the lungs are in |
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Pleurae |
The two layers of membrane round the lungs |
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Parietal pleura |
The layer of membrane that is attached to the body wall, lining the pleural cavity |
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Visceral pleura |
The layer of membrane that is attached to the surface of the lungs, covering them |
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Pleural space |
The space between the visceral and parietal pleurae |
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Pleural fluid |
The fluid in the pleural space |
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Alveolar ventilation |
The amount of air entering the alveoli in one minute |
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Myoglobin |
The protein in red muscle that holds stored oxygen. Made of a protein chain wrapped around a heme group. Can hold one oxygen molecule |
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Hemoglobin |
The protein in red blood cells that carries oxygen. Made of four protein chains, each one wrapped around a heme group. Can carry 4 oxygen molecules. |
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Heme |
A ring of atoms around an iron atom. The part of myoglobin or hemoglobin that holds the oxygen. |
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Alpha and beta chains |
The protein chains that make up normal adult hemoglobin |
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HbA or a2b2 hemoglobin |
Adult hemoglobin, made of two alpha and two beta chains |
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HbF or a2g2
hemoglobin |
Fetal hemoglobin, made of two alpha and two gamma chains |
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Oxygenated hemoglobin |
Hemoglobin that is carrying oxygen - red |
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Deoxygenated hemoglobin |
Hemoglobin that is not carrying oxygen - blue |
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Oxygen saturation |
The amount of oxygen the hemoglobin is carrying, divided by the maximum amount it could possibly carry. Given in %. |
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Oxygen capacity |
The amount of oxygen a blood sample could carry, in mL O2/100 mL of blood |
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Oxygen affinity |
How hard the hemoglobin holds on to the oxygen it has picked up. |
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Oxygen unloading |
When hemoglobin drops oxygen off in the tissues that need it. |
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Oxygen loading |
When hemoglobin picks oxygen up in the lungs. |
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